Biochemical Studies on Amphibian Metamorphosis

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Biochemical Studies on Amphibian Metamorphosis

Thyroxine has been shown to accelerate the synthesis of carbamyl phosphate synthetase in the liver of Rana catesbeiana. Stimulation of carbamyl phosphate synthetase synthesis by thyroxine appears to be relatively specific because of the following observations: (1) succinoxidase activity decreased during the time that carbamyl phosphate synthetase increased; (2) liver catalase responded more slo...

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Biochemical Studies on Amphibian Metamorphosis I. The effect of thyroxine on protein synthesis in the tadpole

Thyroxine has been shown to accelerate the synthesis of carbamyl phosphate synthetase in the liver of Rana catesbdana. Stimulation of carbamyl phosphate synthetase synthesis by thyroxine appears to be relatively specific because of the following observations: (I) succinoxidase activity decreased during the time that carbamyl phosphate synthetase increased; (2) liver catalase responded more slow...

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Biochemical Studies on Amphibian Metamorphosis I. The effect of thyroxine on protein synthesis in the tadpole

Thyroxine has been shown to accelerate the synthesis of carbamyl phosphate synthetase in the liver of Rana catesbdana. Stimulation of carbamyl phosphate synthetase synthesis by thyroxine appears to be relatively specific because of the following observations: (I) succinoxidase activity decreased during the time that carbamyl phosphate synthetase increased; (2) liver catalase responded more slow...

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Biochemical studies on amphibian metamorphosis. III. Metabolism of nucleic acids and nucleotides in tadpole liver during thyroxine-induced metamorphosis.

Previous papers from this laboratory on the biochemical changes occurring during the thyroxine-induced metamorphosis of tadpoles have been concerned primarily with the biosynthesis of carbamyl phosphate synthetase. The acceleration of the synthesis of this enzyme in the presence of this hormone has been shown to be relatively specific and to precede morphological changes. It has been demonstrat...

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Neuroendocrinology of amphibian metamorphosis.

The timing of metamorphosis is a central amphibian life history trait and is controlled by the interplay of developmental progression, body size and condition, and environmental signals. These different processes and signals are integrated by the neuroendocrine system to regulate production of hormones by the thyroid gland. Thyroid hormone (TH) is the primary morphogen controlling metamorphosis...

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ژورنال

عنوان ژورنال: Journal of General Physiology

سال: 1960

ISSN: 1540-7748,0022-1295

DOI: 10.1085/jgp.43.4.683